BDBM293686 3-({[7-(furan-3-yl)-3,4-dihydro-2H-1-benzopyran-4-::US10106534, Example 28

SMILES OC(=O)c1ccncc1NCC1CCOc2cc(ccc12)-c1ccoc1

InChI Key InChIKey=HRIGTZGZYXMXLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293686   

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293686(3-({[7-(furan-3-yl)-3,4-dihydro-2H-1-benzopyran-4-...)
Affinity DataIC50: <100nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293686(3-({[7-(furan-3-yl)-3,4-dihydro-2H-1-benzopyran-4-...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent