BDBM29432 Pyrazolo[1,5-a]-1,3,5-triazine, 12-1

SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1

InChI Key InChIKey=AATALYIJLBSKKQ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29432   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Co.

LigandPNGBDBM29432(Pyrazolo[1,5-a]-1,3,5-triazine, 12-1)
Show SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C20H27N5O3/c1-14-18(16-6-8-17(28-5)9-7-16)19-21-15(2)22-20(25(19)23-14)24(10-12-26-3)11-13-27-4/h6-9H,10-13H2,1-5H3
Affinity DataIC50: 11.5nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair