BDBM295679 US10851091, U.S. Pat. No. 8,242,104 No. 529::US8242104, Compound 529

SMILES C[C@H](Nc1ccc2-c3nc(cn3CCOc2c1)-c1ncnn1CC(F)(F)F)C(N)=O

InChI Key InChIKey=AHNACMAJVLLNSG-JTQLQIEISA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 295679   

LigandPNGBDBM295679(US10851091, U.S. Pat. No. 8,242,104 No. 529 | US82...)
Affinity DataKi:  0.0230nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM295679(US10851091, U.S. Pat. No. 8,242,104 No. 529 | US82...)
Affinity DataKi:  0.0230nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295679(US10851091, U.S. Pat. No. 8,242,104 No. 529 | US82...)
Affinity DataKi:  1.05nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295679(US10851091, U.S. Pat. No. 8,242,104 No. 529 | US82...)
Affinity DataKi:  1.05nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent