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BDBM29844 N-(Pyridin-2-yl) arylsulfonamide, 4

SMILES: CN1CCN(CC1)C(=O)Cc1cccc(NS(=O)(=O)c2cccc(Cl)c2C)n1

InChI Key: InChIKey=YPEJNKQAWSMGFW-UHFFFAOYSA-N

Data: 1 Other

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29844   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM29844
PNG
(N-(Pyridin-2-yl) arylsulfonamide, 4)
Show SMILES CN1CCN(CC1)C(=O)Cc1cccc(NS(=O)(=O)c2cccc(Cl)c2C)n1
Show InChI InChI=1S/C19H23ClN4O3S/c1-14-16(20)6-4-7-17(14)28(26,27)22-18-8-3-5-15(21-18)13-19(25)24-11-9-23(2)10-12-24/h3-8H,9-13H2,1-2H3,(H,21,22)
PDB
MMDB

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Similars

Article
PubMed
n/an/an/an/an/an/an/a8.022



Pfizer Inc



Assay Description
The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...


Bioorg Med Chem Lett 19: 3493-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.011
BindingDB Entry DOI: 10.7270/Q2SB4428
More data for this
Ligand-Target Pair