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BDBM298546 US10125111, Compound 4002

SMILES: CNC(=O)c1c(oc2cc(N(CCCF)S(C)(=O)=O)c(cc12)-c1cccc(c1)C(O)=O)-c1ccc(F)cc1

InChI Key: InChIKey=UCOZWZYONZFYRG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298546   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM298546
PNG
(US10125111, Compound 4002)
Show SMILES CNC(=O)c1c(oc2cc(N(CCCF)S(C)(=O)=O)c(cc12)-c1cccc(c1)C(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C27H24F2N2O6S/c1-30-26(32)24-21-14-20(17-5-3-6-18(13-17)27(33)34)22(31(12-4-11-28)38(2,35)36)15-23(21)37-25(24)16-7-9-19(29)10-8-16/h3,5-10,13-15H,4,11-12H2,1-2H3,(H,30,32)(H,33,34)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+3n/an/an/an/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...


US Patent US10125111 (2018)


BindingDB Entry DOI: 10.7270/Q2PC34GP
More data for this
Ligand-Target Pair