BDBM29987 benzimidazole analogue, 7e::benzimidazole derivative, 1

SMILES CCN1CCN(CC1)c1cc2[nH]c(S[C@@]3(C)CC[C@@H](CC3)NC(=O)OC)nc2cc1Cl

InChI Key InChIKey=ZMCNDHKXQWQHCC-VVONHTQRSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29987   

TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29987(benzimidazole analogue, 7e | benzimidazole derivat...)
Affinity DataIC50:  2.40nM EC50:  0.720nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29987(benzimidazole analogue, 7e | benzimidazole derivat...)
Affinity DataIC50:  3.50E+3nMAssay Description:Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29987(benzimidazole analogue, 7e | benzimidazole derivat...)
Affinity DataIC50:  2.40nM EC50:  0.720nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed