BDBM300525 3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)-N-(5-phenylpyridin-2-yl)-4-(trifluoromethoxy)benzamide::US10130633, Example 95

SMILES FC(F)(F)Oc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(cn1)-c1ccccc1

InChI Key InChIKey=MCDAQFFHHGMCAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300525   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300525(3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)...)
Affinity DataIC50:  58.1nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300525(3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)...)
Affinity DataIC50: >5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300525(3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)...)
Affinity DataIC50:  50nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300525(3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}amino)...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent