BDBM301314 3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-1-methyl-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one::US10131667, Example 130::US11053246, Example 130::US9611267, Example 130

SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(CN5CCN(CCO)CC5)cc4c3N(C)C2=O)c1F

InChI Key InChIKey=LACFWZYGHLLJOI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 301314   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM301314(3-(2,6-difluoro-3,5-dimethoxyphenyl)-8-{[4-(2-hydr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent