BindingDB logo
myBDB logout

BDBM30233 carboline analog, 45

SMILES: CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1Br

InChI Key: InChIKey=LZFAKIYGNFRNII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30233   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (Human))
BDBM30233
PNG
(carboline analog, 45)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1Br
Show InChI InChI=1S/C19H16BrN3O2/c1-10-9-21-19(25)17-16(10)12-8-11(6-7-14(12)22-17)18(24)23-15-5-3-2-4-13(15)20/h2-8,10,22H,9H2,1H3,(H,21,25)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair