BDBM304040 US10138245, Example 48A

SMILES Cc1cc(C)n2nc(nc2n1)-c1ccc2n(C)c(nc2c1)-c1ccccc1

InChI Key InChIKey=PAJYRGIEPUAUJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304040   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM304040(US10138245, Example 48A)
Affinity DataIC50:  794nMAssay Description:Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE10A1 expressed in baculovirus infected Sf9 cells using c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM304040(US10138245, Example 48A)
Affinity DataIC50:  794nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent