BDBM304042 US10138245, Example 56
SMILES Cc1cc(C)n2nc(nc2n1)-c1ccn2cc(nc2n1)-c1ccccc1
InChI Key InChIKey=NGJSCTGVOICSBG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 304042
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Celon Pharma
US Patent
Celon Pharma
US Patent
Affinity DataIC50: 96nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Celon Pharma
US Patent
Celon Pharma
US Patent
Affinity DataIC50: 96nMAssay Description:Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE10A1 expressed in baculovirus infected Sf9 cells using c...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Homo sapiens (Human))
Celon Pharma
Curated by ChEMBL
Celon Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ca2+/calmodulin-induced full-length recombinant human N-terminal GST-tagged PDE1C expressed in baculovirus infected Sf9 insect cells us...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Celon Pharma
Curated by ChEMBL
Celon Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE9A2 expressed in baculovirus infected Sf9 cells using cG...More data for this Ligand-Target Pair