BDBM304502 (R)-(4-(3-isopropyl-4-(6-(trifluoromethyl)pyridin-3-yl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 20-4

SMILES CC(C)[C@@H]1CN(CCN1c1ccc(nc1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O

InChI Key InChIKey=UTDAXXUUCUHZOH-SFHVURJKSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304502   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304502((R)-(4-(3-isopropyl-4-(6-(trifluoromethyl)pyridin-...)
Affinity DataKi:  20nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304502((R)-(4-(3-isopropyl-4-(6-(trifluoromethyl)pyridin-...)
Affinity DataKi:  41nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent