BDBM304609 (S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-4

SMILES CC1(C)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=OCSBWUNDZQJSRW-XMMPIXPASA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 304609   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304609((S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methy...)
Affinity DataKi:  10nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304609((S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methy...)
Affinity DataKi:  39nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304609((S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methy...)
Affinity DataEC50:  18nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304609((S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methy...)
Affinity DataEC50:  301nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent