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BDBM308408 US9649309, Compound UNC2062A

SMILES: CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCCN2CCOCC2)n1

InChI Key: InChIKey=HINDSEFQAAOHIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM308408
PNG
(US9649309, Compound UNC2062A)
Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCCN2CCOCC2)n1
Show InChI InChI=1S/C25H37N7O5S/c1-2-3-8-27-25-28-19-22(23(30-25)26-9-10-31-11-15-36-16-12-31)24(33)29-20-4-6-21(7-5-20)38(34,35)32-13-17-37-18-14-32/h4-7,19H,2-3,8-18H2,1H3,(H,29,33)(H2,26,27,28,30)
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US Patent
n/an/a 550n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)


BindingDB Entry DOI: 10.7270/Q26Q209H
More data for this
Ligand-Target Pair