BDBM309935 1-(3,4- dimethoxybenzyl)-3- (1H- benzo[d]imidazol-5- yl)thiourea::US9656991, 49

SMILES COc1ccc(CNC(=S)Nc2ccc3[nH]cnc3c2)cc1OC

InChI Key InChIKey=GVRHCRQDLQLLDH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309935   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM309935(1-(3,4- dimethoxybenzyl)-3- (1H- benzo[d]imidazol-...)
Affinity DataKi:  29nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM309935(1-(3,4- dimethoxybenzyl)-3- (1H- benzo[d]imidazol-...)
Affinity DataIC50:  218nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent