BDBM309976 (S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-5-carboxamide::US11046713, Example 219::US9657003, 34

SMILES C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1cc(n[nH]1)C(C)=O

InChI Key InChIKey=GMBPVBVTPBWIKC-NSHDSACASA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 309976   

TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  16nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataKi:  40nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataIC50:  146nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataIC50:  172nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309976((S)-3-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-p...)
Affinity DataIC50:  172nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In DepthDetails US Patent