BDBM309980 N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)ethyl)-3-(pyridin-3-yl)-1H-pyrazole-5-carboxamide::US11046713, Example 53::US9657003, 53

SMILES Cc1cc(ccc1C#N)-c1ccn(CCNC(=O)c2cc(n[nH]2)-c2cccnc2)n1

InChI Key InChIKey=FNVPYXFLSDVEKH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309980   

TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataKi:  18nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataKi:  18nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataIC50:  88nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM309980(N-(2-(3-(4-cyano-3-methylphenyl)-1H-pyrazol-1-yl)e...)
Affinity DataIC50:  88nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent