BDBM31092 US8853193, 32-33

SMILES Cc1c(sc2ncnc(Nc3ccc(F)cc3OCCO)c12)C(=O)NCCO

InChI Key InChIKey=KDKUVYLMPJIGKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31092   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM31092(US8853193, 32-33)
Affinity DataIC50:  65nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In DepthDetails US Patent