BDBM31148 3-hydroxyquinolin-2(1H)-one, 2::US9701638, 1
SMILES Oc1cc2ccccc2[nH]c1=O
InChI Key InChIKey=BERPCVULMUPOER-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 31148
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 855nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H activityMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reade...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of DAAO (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 2.40E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to pig kidney DAAO by ITC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of rat spinal DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair