BDBM312202 US9604926, Compound CM-397::US9724435, Compound CM-397

SMILES Cn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O

InChI Key InChIKey=ZHOKGRSOBIVAGC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 312202   

TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University Of Mississippi

US Patent
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  0.460nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  0.460nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University Of Mississippi

US Patent
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat brain membranes after 120 mins in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  366nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain membranes after 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  415nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312202(US9604926, Compound CM-397 | US9724435, Compound C...)
Affinity DataKi:  415nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent