BDBM312787 6-chloro-1-[3-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-pyrroli- din-3-yl]ethynyl]phenyl] pyrazolo[4,3-c]pyridine-3- carboxamide::US9605005, Example 76
SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cnc(Cl)cc23)C1=O
InChI Key InChIKey=DJEIIOBJWIKKRM-FQEVSTJZSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312787
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair