BDBM312806 1,7-bis[3-[2-[(3R)-3-hydroxy- 1-methyl-2-oxo-pyrrolidin- 3-yl]ethynyl]phenyl]imi- dazo[1,5-a]pyridine-3-carbox- amide::US9605005, Example 95
SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-c2nc(C(N)=O)n3ccc(cc23)-c2cccc(c2)C#C[C@]2(O)CCN(C)C2=O)C1=O
InChI Key InChIKey=ZINMBKKZSSTZHG-HEVIKAOCSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312806
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair