BDBM312906 1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]phenyl]-5-(meth- ylamino)pyrazolo[3,4-d]thia- zole-3-carboxamide::US9605005, Example 196
SMILES CNc1nc2n(nc(C(N)=O)c2s1)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O
InChI Key InChIKey=AAVCEDJAQUYSLX-IBGZPJMESA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312906
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair