BDBM31523 Compound 6::Naphthalene and Benzamide Derivative, 24::med.21724, Compound 162

SMILES C[C@@H](NC(=O)c1cc(NC(C)=O)ccc1C)c1cccc2ccccc12

InChI Key InChIKey=KGPYBLOBHQLIET-OAHLLOKOSA-N

Data  4 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 31523   

TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  560nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  5.00E+3nMAssay Description:Emulating Ratia et al., who detailed the potency of these four compounds against SARS-CoV-1, we utilized the peptide-AMC substrate concentration of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of N-terminal His/TEV-tagged SARS-CoV-2 papain-like protease nsp3 (746 to 1060 residues) expressed in Escherichia coli BL21 (DE3) using (Z...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
University Of Bonn

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  560nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataEC50:  2.10E+4nMAssay Description:Emulating Ratia et al., who detailed the potency of these four compounds against SARS-CoV-1, we utilized the peptide-AMC substrate concentration of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed