BDBM318937 US10173988, Compound B

SMILES COc1cccc(c1)N1CCN(Cc2nc(N)nc(Nc3ccc(C)c(Cl)c3)n2)CC1

InChI Key InChIKey=MLLJHBXGHWWNFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 318937   

TargetNADPH oxidase 1(Homo sapiens (Human))
Glucox Biotech

US Patent
LigandPNGBDBM318937(US10173988, Compound B)
Affinity DataIC50:  2.20E+4nMAssay Description:CHO cells modified to stably express human Nox1 were grown in DMEM/F12 gibco 31331 containing 10% FBS and 1% pen/strep at 37° C. in air with 5% CO2. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNADPH oxidase 4(Homo sapiens (Human))
Glucox Biotech

US Patent
LigandPNGBDBM318937(US10173988, Compound B)
Affinity DataIC50:  840nMAssay Description:Cells: HEK (CJ Nox4) stably expressing Nox4 was purchased from Redoxis AB (Lund). The adherent cells were cultivated in RPMI 1640 with L-Glutamine we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Glucox Biotech

US Patent
LigandPNGBDBM318937(US10173988, Compound B)
Affinity DataIC50:  1.70E+4nMAssay Description:Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we...More data for this Ligand-Target Pair
In DepthDetails US Patent