BDBM319624 7-(2-(4-(2,3-dihydrobenzo[b]thiophen-4-yl)piperazin-1-yl)ethyl)quinolin-2(1H)-one::US10174011, Example 25

SMILES O=c1ccc2ccc(CCN3CCN(CC3)c3cccc4SCCc34)cc2[nH]1

InChI Key InChIKey=KXADBRPCRIFTTK-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319624   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319624(7-(2-(4-(2,3-dihydrobenzo[b]thiophen-4-yl)piperazi...)
Affinity DataEC50:  0.824nMAssay Description:The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319624(7-(2-(4-(2,3-dihydrobenzo[b]thiophen-4-yl)piperazi...)
Affinity DataIC50:  77.9nMAssay Description:The 5-HT2A receptor antagonism activity test (The antagonism activity of test compounds on 5-HT2A receptor expressing human recombinant 5-HT2A recept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319624(7-(2-(4-(2,3-dihydrobenzo[b]thiophen-4-yl)piperazi...)
Affinity DataIC50:  85.1nMAssay Description:The D2 receptor antagonism activity test (The antagonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent