BDBM322274 7-chloro-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound 56a

SMILES Clc1cccc2cc(sc12)C(=O)NC1C2CCN(CC2)C11CC1

InChI Key InChIKey=HIQWVKZIJAMSHI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322274   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322274(7-chloro-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[...)
Affinity DataKi:  37nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322274(7-chloro-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[...)
Affinity DataKi:  48nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent