BDBM323036 1-Ethyl-4-[({(1R,2R)-2-[4-(3-methyl-1H- pyrazol-5-yl)benzoyl]cyclohexyl}- carbonyl)amino]-1H-pyrazole-5- carboxamide::US10183947, Example 19::US10508119, Example 19::US11001589, Example 19::US11691978, Example 19
SMILES CCn1ncc(NC(=O)[C@@H]2CCCC[C@H]2C(=O)c2ccc(cc2)-c2cc(C)n[nH]2)c1C(N)=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 323036
Affinity DataIC50: 29nMAssay Description:Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by microbeta scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair