BDBM323036 1-Ethyl-4-[({(1R,2R)-2-[4-(3-methyl-1H- pyrazol-5-yl)benzoyl]cyclohexyl}- carbonyl)amino]-1H-pyrazole-5- carboxamide::US10183947, Example 19::US10508119, Example 19::US11001589, Example 19::US11691978, Example 19

SMILES CCn1ncc(NC(=O)[C@@H]2CCCC[C@H]2C(=O)c2ccc(cc2)-c2cc(C)n[nH]2)c1C(N)=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323036   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM323036(1-Ethyl-4-[({(1R,2R)-2-[4-(3-methyl-1H- pyrazol-5-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by microbeta scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM323036(1-Ethyl-4-[({(1R,2R)-2-[4-(3-methyl-1H- pyrazol-5-...)
Affinity DataIC50:  29nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent