BDBM32308 (Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one::(Z)-1-phenyl-3-(5-phenyl-2-furyl)prop-2-en-1-one::(Z)-1-phenyl-3-(5-phenylfuran-2-yl)prop-2-en-1-one::MLS000722313::SMR000236018::cid_5708162

SMILES O=C(\C=C/c1ccc(o1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=ATYVZTGIQBANCN-QBFSEMIESA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32308   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataEC50:  9.36E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataEC50:  1.06E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM23(Saccharomyces cerevisiae S288c)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataIC50:  3.01E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataEC50:  2.07E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Saccharomyces cerevisiae S288c)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataIC50:  5.47E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32308((Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one...)
Affinity DataEC50:  3.49E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay