BDBM323419 (R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-Ol::US10188615, Example 28::US10639286, Example 28

SMILES NCC[C@@H](O)c1cccc(OCC2CCCCC2)c1

InChI Key InChIKey=WJIGGYYSZBWCGC-MRXNPFEDSA-N

Data  4 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323419   

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandPNGBDBM323419((R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinaldehyde-binding protein 1(Human)
Acucela

US Patent
LigandPNGBDBM323419((R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetRetinaldehyde-binding protein 1(Bovine)
Acucela

US Patent
LigandPNGBDBM323419((R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetRetinoid isomerohydrolase(Bovine)
Acucela

US Patent
LigandPNGBDBM323419((R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair