BDBM323668 N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- ethoxyphenoxy)piperidin- 1-yl)pyrimidine-5- carboxamide::US10188653, Example 21.1::US9789110, 21.1

SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)N[C@H]1CCc2ccccc12

InChI Key InChIKey=QPJCECGFQKAFEJ-GGAORHGYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323668   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323668(N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...)
Affinity DataIC50:  1.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323668(N-((S)-2,3-dihydro-1H- inden-1-yl)-2-((R)-3-(2- et...)
Affinity DataIC50:  1.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent