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BDBM325056 9-((4'-(2-(dimethylamino)ethyl)-[1,1'-biphenyl]-4-::US10189841, Compound I-262

SMILES: CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3ccc(CCN(C)C)cc3)c2n1

InChI Key: InChIKey=UUEGAEKNKKQXIW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325056   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1


(Homo sapiens (Human))
BDBM325056
PNG
(9-((4'-(2-(dimethylamino)ethyl)-[1,1'-biphenyl]-4-...)
Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3ccc(CCN(C)C)cc3)c2n1
Show InChI InChI=1S/C32H35N5O/c1-22(2)27-8-6-7-9-28(27)30-33-20-29-31(34-30)37(32(38)36(29)5)21-24-12-16-26(17-13-24)25-14-10-23(11-15-25)18-19-35(3)4/h6-17,20,22H,18-19,21H2,1-5H3
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 125n/an/an/an/an/an/a



Forma Therapeutics Inc

US Patent


Assay Description
The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...


US Patent US10189841 (2019)


BindingDB Entry DOI: 10.7270/Q22R3TRR
More data for this
Ligand-Target Pair