BDBM32550 arylsulfonylpiperazine, 22

SMILES FC(F)(F)c1cccnc1N1CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=BNPWQWJVBHTYKU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32550   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Amgen

LigandPNGBDBM32550(arylsulfonylpiperazine, 22)
Affinity DataIC50:  25nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32550(arylsulfonylpiperazine, 22)
Affinity DataIC50:  7nM EC50:  241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed