BDBM32689 (3-Furan-2-ylmethyl-8-methyl-3,4-dihydro-1-thia-3,9-diaza-anthracen-2-ylidene)-(2-methoxy-ethyl)-amine::3-(2-furanylmethyl)-N-(2-methoxyethyl)-9-methyl-4H-[1,3]thiazino[6,5-b]quinolin-2-imine::3-(furan-2-ylmethyl)-N-(2-methoxyethyl)-9-methyl-4H-[1,3]thiazino[6,5-b]quinolin-2-imine::MLS000067793::SMR000122349::[3-(2-furfuryl)-9-methyl-4H-[1,3]thiazino[6,5-b]quinolin-2-ylidene]-(2-methoxyethyl)amine::cid_3213217

SMILES COCC\N=C1/Sc2nc3c(C)cccc3cc2CN1Cc1ccco1

InChI Key InChIKey=FIUFLAMLZBCURL-MRCUWXFGSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32689   

TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32689((3-Furan-2-ylmethyl-8-methyl-3,4-dihydro-1-thia-3,...)
Affinity DataIC50:  745nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32689((3-Furan-2-ylmethyl-8-methyl-3,4-dihydro-1-thia-3,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32689((3-Furan-2-ylmethyl-8-methyl-3,4-dihydro-1-thia-3,...)
Affinity DataEC50:  2.30E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32689((3-Furan-2-ylmethyl-8-methyl-3,4-dihydro-1-thia-3,...)
Affinity DataIC50:  745nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay