BDBM327943 N-(1-benzylpiperidin-4- yl)-5-(4-((5- methylisoxazol-3- yl)methyl)piperazine-1- carbonyl)picolinamide::US10377742, Compound 85::US9663496, Compound 85

SMILES Cc1cc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)NC2CCN(Cc3ccccc3)CC2)no1

InChI Key InChIKey=GWJLUAVBJOJUAI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327943   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327943(N-(1-benzylpiperidin-4- yl)-5-(4-((5- methylisoxaz...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327943(N-(1-benzylpiperidin-4- yl)-5-(4-((5- methylisoxaz...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent