BDBM32813 2-(2-chlorophenyl)-4-thieno[3,2-d][1,3]oxazinone::2-(2-chlorophenyl)-4H-thieno[3,2-d][1,3]oxazin-4-one::2-(2-chlorophenyl)thieno[3,2-d][1,3]oxazin-4-one::MLS000541266::SMR000126124::cid_1485389

SMILES Clc1ccccc1-c1nc2ccsc2c(=O)o1

InChI Key InChIKey=RVSYWOORIBXTII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32813   

TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32813(2-(2-chlorophenyl)-4-thieno[3,2-d][1,3]oxazinone |...)
Affinity DataIC50:  241nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32813(2-(2-chlorophenyl)-4-thieno[3,2-d][1,3]oxazinone |...)
Affinity DataIC50:  241nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32813(2-(2-chlorophenyl)-4-thieno[3,2-d][1,3]oxazinone |...)
Affinity DataIC50:  440nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay