BDBM32934 MLS000419584::N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)-2-furamide::N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)-2-furancarboxamide::N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)furan-2-carboxamide::SMR000320301::cid_7202802

SMILES O=C(Nc1nc2cc3OCOc3cc2s1)c1ccco1

InChI Key InChIKey=GLLWHIMOHBWLKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32934   

TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32934(MLS000419584 | N-([1,3]dioxolo[4,5-f][1,3]benzothi...)
Affinity DataIC50:  9.57E+3nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32934(MLS000419584 | N-([1,3]dioxolo[4,5-f][1,3]benzothi...)
Affinity DataIC50:  2.81E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32934(MLS000419584 | N-([1,3]dioxolo[4,5-f][1,3]benzothi...)
Affinity DataIC50:  455nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32934(MLS000419584 | N-([1,3]dioxolo[4,5-f][1,3]benzothi...)
Affinity DataIC50:  518nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay