BDBM329432 2-(4-Methyl-5-(2-methyl- 4-(((1S,2S)-2-(5- methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidin-5-yl)pyridin-2- yl)propan-2-ol::US9663513, 45

SMILES Cc1ccc(nc1)C1C[C@@H]1COc1nc(C)ncc1-c1cnc(cc1C)C(C)(C)O

InChI Key InChIKey=BKVAQLSKJIVYPC-QNSVNVJESA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329432   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329432(2-(4-Methyl-5-(2-methyl- 4-(((1S,2S)-2-(5- methylp...)
Affinity DataKi:  0.0200nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent