BDBM332445 4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- morpholino-1H- indazol-3-yl) benzoic acid::US10196354, Example 4H::US9745265, 4H
SMILES OC(=O)c1ccc(cc1)-c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cc(ccc12)N1CCOCC1
InChI Key InChIKey=PAOBWZISCVUZCX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332445
Affinity DataIC50: 4.32E+3nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 4.32E+3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair