BDBM332503 4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbonyl}-6- (4-fluorophenyl)- 1H-indazol-3-yl]benzoic acid::US10196354, Example 23I::US9745265, 23I

SMILES OC(=O)c1ccc(cc1)-c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cc(ccc12)-c1ccc(F)cc1

InChI Key InChIKey=JHZRWXUYINHMEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332503   

TargetNuclear receptor ROR-gamma(Mus musculus)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332503(4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...)
Affinity DataIC50: >1.00E+4nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332503(4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...)
Affinity DataIC50: >1.00E+4nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent