BDBM332703 US10196378, Compound C06
SMILES CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccc5cccnc5c4)cc3)cc2C(F)(F)F)CC1
InChI Key InChIKey=RVQLPYKLAJLXMV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 332703
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 2nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 2nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 4nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 6.20nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 1.20E+4nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: 637nMAssay Description:Inhibition of NanoLuc-tagged ABL1 wild type (unknown origin) expressed in HEK293 cells by NanoBRET TE assayMore data for this Ligand-Target Pair