BDBM33415 CHEMBL204900::pyrimidinol carboxylic acid, 7

SMILES OC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O

InChI Key InChIKey=KKFDSUVIQPBLJU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33415   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences

LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)
Affinity DataIC50:  2.50E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed