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BDBM3348 4-N-{[3-(dimethylamino)phenyl]methyl}pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8r::7-amino-4-[ [ [3-( dimethylamino)phenyl]methyl]amino]pyrido[4,3-d]pyrimidine

SMILES: CN(C)c1cccc(CNc2ncnc3cc(N)ncc23)c1

InChI Key: InChIKey=NUNYTOSAJZDUSJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3348
PNG
(4-N-{[3-(dimethylamino)phenyl]methyl}pyrido[4,3-d]...)
Show SMILES CN(C)c1cccc(CNc2ncnc3cc(N)ncc23)c1
Show InChI InChI=1S/C16H18N6/c1-22(2)12-5-3-4-11(6-12)8-19-16-13-9-18-15(17)7-14(13)20-10-21-16/h3-7,9-10H,8H2,1-2H3,(H2,17,18)(H,19,20,21)
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MMDB

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Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 38: 3780-8 (1995)


Article DOI: 10.1021/jm00019a007
BindingDB Entry DOI: 10.7270/Q2Z899M8
More data for this
Ligand-Target Pair