BDBM335080 3-[4-[(S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-yl)-2-methyl-pyrrolidine-1-carbonyl]-5-(4-fluoro-phenyl)-thiazol-2-yl]-benzonitrile::US11040966, Example 5.255::US9732075, Example 5.255

SMILES Cc1c(Cl)ccc2[nH]c(nc12)[C@]1(C)CCCN1C(=O)c1nc(sc1-c1ccc(F)cc1)-c1cccc(c1)C#N

InChI Key InChIKey=RGQDQGMCUZKIIP-PMERELPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335080   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335080(3-[4-[(S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-...)
Affinity DataIC50:  145nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335080(3-[4-[(S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-...)
Affinity DataIC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent