BDBM335369 US11040966, Example 7.33::US9732075, Example 7.33::[(S)-2-(5-Chloro-1,4-dimethyl-1H-benzoimidazol-2-yl)-2-methyl-pyrrolidin-1-yl]-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone and/or [(S)-2-(3-Chloro-1,2-dimethyl-1H-benzoimidazol-2-yl)-2-methyl-pyrrolidin-1-yl]-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone (mixtures of isomers)

SMILES Cc1nc(C(=O)N2CCC[C@@]2(C)c2nc3c(C)c(Cl)ccc3n2C)c(s1)-c1cccc(Cl)c1

InChI Key InChIKey=JHGRYXUHXJQVFP-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335369   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335369(US11040966, Example 7.33 | US9732075, Example 7.33...)
Affinity DataIC50:  3nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335369(US11040966, Example 7.33 | US9732075, Example 7.33...)
Affinity DataIC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent