BDBM336140 US9738658, Example 22

SMILES CCCn1ccc2cc(cc(C3CC3)c12)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1c(Cl)ncnc1Cl

InChI Key InChIKey=XNDUBLDQKWAFNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336140   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM336140(US9738658, Example 22)
Affinity DataIC50:  1.80nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent