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BDBM336334 US9744172, Compound UNC00000554A

SMILES: NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCc4ccc(cc4)-c4ccccc4)nc23)CC1

InChI Key: InChIKey=ODAGNAYGJHXJGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336334   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336334
PNG
(US9744172, Compound UNC00000554A)
Show SMILES NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCc4ccc(cc4)-c4ccccc4)nc23)CC1
Show InChI InChI=1S/C31H32N6/c32-27-17-13-23(14-18-27)21-37-30-28(29(36-37)26-9-5-2-6-10-26)20-34-31(35-30)33-19-22-11-15-25(16-12-22)24-7-3-1-4-8-24/h1-12,15-16,20,23,27H,13-14,17-19,21,32H2,(H,33,34,35)
PDB
MMDB

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PC sid
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US Patent
n/an/a 550n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)


BindingDB Entry DOI: 10.7270/Q2PR7Z30
More data for this
Ligand-Target Pair