BindingDB logo
myBDB logout

BDBM340871 US9765054, Compound 28G

SMILES: ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=QNOKUAAIIQQOHF-MGPQQGTHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340871   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))
BDBM340871
PNG
(US9765054, Compound 28G)
Show SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C16H13F3N2O2/c17-16(18,19)11-8-10(6-7-20-11)13-12(14(13)15(22)21-23)9-4-2-1-3-5-9/h1-8,12-14,23H,(H,21,22)/t12-,13-,14-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



CHDI Foundation Inc

US Patent


Assay Description
5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...


US Patent US9765054 (2017)


BindingDB Entry DOI: 10.7270/Q2XW4MZG
More data for this
Ligand-Target Pair