BDBM34110 glucopyranosylidene-spiro-isoxazoline, 4e
SMILES OC[C@H]1O[C@@]2(CC(=NO2)c2ccc3ccccc3c2)[C@H](O)[C@@H](O)[C@@H]1O
InChI Key InChIKey=YKACTKXMYNIMHP-UYTYNIKBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 34110
Affinity DataKi: 630nM ΔG°: -8.59kcal/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Binding affinity to rabbit muscular GPb by NMR binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of glycogen phosphorylase in human hepatocytes assessed as glucagon stimulated glycogen content after 3 hrs by colorimetric GOD methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of glycogen phosphorylase in Wistar rat hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of glycogen phosphorylase in human hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxidase ...More data for this Ligand-Target Pair