BDBM34142 2-ethyl-5-methoxy-N,N-dimethyltryptamine::CHEMBL267615::EDMT::EMDT::[2-(2-ethyl-5-methoxy-1H-indol-3-yl)ethyl]dimethylamine, 6

SMILES CCc1[nH]c2ccc(OC)cc2c1CCN(C)C

InChI Key InChIKey=ZEYRDXUWJDGTLD-UHFFFAOYSA-N

Data  19 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 34142   

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nM ΔG°:  -11.1kcal/molepH: 7.4 T: 37°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human 5-HT6 receptor transfected in HEK293 cells after 60 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  52nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for its binding affinity towards human human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  290nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  300nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  520nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  1.81E+3nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 5A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  4.62E+3nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards human NET(norepinephrine) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1D(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in calfMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  85nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2A receptor in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 7 receptor in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2C receptor in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 3A(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  44nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataIC50:  85nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor stably expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed